Ultrasound-assisted Strecker synthesis of novel 2-(hetero)aryl-2-(arylamino)acetonitrile derivatives

• Emese Gal,
• Luiza Gaina,
• Hermina Petkes,
• Alexandra Pop,
• Castelia Cristea,
• Gabriel Barta,
• Dan Cristian Vodnar and
• Luminiţa Silaghi-Dumitrescu

Beilstein J. Org. Chem. 2020, 16, 2929–2936, doi:10.3762/bjoc.16.242

• , ferrocene or benzene units was screened by the Salmonella mutagenicity assay (Ames test) [28] using S. typhimurium TA98 and TA100 strains. Results and Discussions Ultrasound-assisted synthesis The Strecker reaction between (hetero)aromatic aldimines and TMSCN in poly(ethylene glycol) (PEG)–water medium [18

• synthetic compounds. Conclusion An efficient reaction protocol for the ultrasound-assisted synthesis of new 2-(arylamino)-2-(hetero)arylacetonitrile derivatives containing phenothiazine units was developed. It was proved that the protocol can be more generally applied, affording excellent yields of the

5-Aminopyrazole as precursor in design and synthesis of fused pyrazoloazines

• Ranjana Aggarwal and
• Suresh Kumar

Beilstein J. Org. Chem. 2018, 14, 203–242, doi:10.3762/bjoc.14.15

1-Imidoalkylphosphonium salts with modulated C_α–P⁺ bond strength: synthesis and application as new active α-imidoalkylating agents

• Jakub Adamek,
• Roman Mazurkiewicz,
• Anna Węgrzyk and
• Karol Erfurt

Beilstein J. Org. Chem. 2017, 13, 1446–1455, doi:10.3762/bjoc.13.142

• the product was isolated by column chromatography (toluene/ethyl acetate 10:1, v/v). The crude crystalline compounds 9aa, 9ab, 9bb, 9ia were recrystallized from toluene or toluene/hexane 1:1, v/v. Ultrasound assisted synthesis of N-(1-arylalkyl)imides 9: A suspension of 1-(N-imido

Features of the behavior of 4-amino-5-carboxamido-1,2,3-triazole in multicomponent heterocyclizations with carbonyl compounds

• Eugene S. Gladkov,
• Katerina A. Gura,
• Svetlana M. Sirko,
• Sergey M. Desenko,
• Ulrich Groth and
• Valentin A. Chebanov

Beilstein J. Org. Chem. 2012, 8, 2100–2105, doi:10.3762/bjoc.8.236

• ; heterocycle; microwave-assisted synthesis; multicomponent reaction; ultrasound-assisted synthesis; Introduction Multicomponent reactions (MCRs) [1][2][3][4] involving polyfunctional aminazoles as a key reagent are challenging objectives in the modern chemistry of heterocyclic compounds dealing with the

Cyclodextrin-based nanosponges as drug carriers

• Francesco Trotta,
• Marco Zanetti and
• Roberta Cavalli

Beilstein J. Org. Chem. 2012, 8, 2091–2099, doi:10.3762/bjoc.8.235

• the Boson peak and Brillouin frequency [16]. Using ultrasound-assisted synthesis and a suitable cross-linker molar ratio, spherical nanosponges of submicron size were obtained [17]. The cross-linking produces a powder consisting of cyclodextrin connected by nanochannels to form a cage-like structure